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BIOGF 331 – Sterilia 5ml

  • Delivery & Return

Description

Multi-Axis Dermal Biostimulation

A sterile formulation engineered to optimize skin quality through the synergistic combination of human-like growth factors (EGF, TGF-β2, and VEGF) together with human-like biomimetic fragments of Collagen I, Collagen IV, and Fibrillin-1.

The formula also incorporates Skinarch™, an advanced modulator of fibrillar collagen architecture designed to support matrix organization and dermal integrity.

This comprehensive approach targets the three essential pillars of aesthetic regeneration:

  • Cellular signaling
  • Structural substrate support
  • Extracellular matrix organization

In both intrinsic aging and photoaging, there is a progressive reduction in collagen synthesis, increased degradation by Matrix Metalloproteinases (MMPs), oxidative stress accumulation, and deterioration of the dermal-epidermal junction (DEJ).

BIOGF 331 is designed as an adjuvant solution to help restore skin density, firmness, and elasticity while improving the coherence and quality of clinical outcomes when integrated into multi-modality professional protocols.

Professional Use Only

Multi-Component Biostimulating Cocktail developed for dermal remodeling and optimization of the dermal-epidermal junction.

Indicated as an adjuvant within professional rejuvenation protocols targeting:

  • Photoaging
  • Loss of density
  • Incipient skin laxity
  • Fine lines
  • Irregular skin texture

It may also be incorporated into combined professional plans designed for:

  • Atrophic acne scars
  • Stretch marks

Use according to professional clinical evaluation and discretion.

Presentation

5 ml single-dose sterile vial
Box containing 5 sterile vials.

Professional Guidelines

Recommended protocol:

  • Fortnightly sessions for 2 months
  • 1 vial per session
  • From the third month onward, maintenance according to clinical response and professional prescription

Ingredients

Active Ingredients

  • Human-like Growth Factors:
    EGF, TGF-β2, and VEGF work synergistically to support epidermal renewal, dermal remodeling, fibroblast activity, and tissue revitalization.
  • Human-like Biomimetic Fragments:
    Collagen I, Collagen IV, and Fibrillin-1 provide structural support and help reinforce dermal-epidermal cohesion, elasticity, and matrix organization.
  • Skinarch™ Peptide:
    Advanced peptide technology designed to support fibrillar collagen architecture, promoting improved firmness, skin density, and structural integrity.

Technology

Technology & Mechanism of Action

BIOGF 331 integrates active ingredients with complementary biological targets designed to support dermal regeneration, matrix organization, and overall skin quality optimization.

  • Epidermal Signaling (EGF):
    Supports epidermal renewal processes and reinforces skin barrier function, contributing to smoother, healthier-looking skin.
  • Dermal Signaling (TGF-β2):
    Helps modulate fibroblast activity and supports extracellular matrix synthesis, promoting improved dermal structure and firmness.
  • Microvascular Support (VEGF):
    Contributes to a favorable tissue microenvironment that supports repair, remodeling, and skin revitalization processes.
  • Biomimetic Structural Fragments:
    Human-like Collagen I, Collagen IV, and Fibrillin-1 provide structural “building blocks” and anchoring points that help reinforce mechanotransduction and dermal-epidermal cohesion.
  • Skinarch™ Technology:
    Acts as a fibrillar collagen “architect,” promoting better-organized collagen fibers through the Mohawk signaling axis and Collagen VI support, helping optimize dermal structure and elasticity.

Expected Clinical Outcome

  • Progressive improvement in dermal firmness and density
  • Optimization of skin texture and luminosity through reinforcement of the dermal-epidermal junction (DEJ)
  • Enhanced skin elasticity and “bounce” through support of the elastic fiber network
  • Improved overall skin quality and structural coherence

Description

Multi-Axis Dermal Biostimulation

A sterile formulation engineered to optimize skin quality through the synergistic combination of human-like growth factors (EGF, TGF-β2, and VEGF) together with human-like biomimetic fragments of Collagen I, Collagen IV, and Fibrillin-1.

The formula also incorporates Skinarch™, an advanced modulator of fibrillar collagen architecture designed to support matrix organization and dermal integrity.

This comprehensive approach targets the three essential pillars of aesthetic regeneration:

  • Cellular signaling
  • Structural substrate support
  • Extracellular matrix organization

In both intrinsic aging and photoaging, there is a progressive reduction in collagen synthesis, increased degradation by Matrix Metalloproteinases (MMPs), oxidative stress accumulation, and deterioration of the dermal-epidermal junction (DEJ).

BIOGF 331 is designed as an adjuvant solution to help restore skin density, firmness, and elasticity while improving the coherence and quality of clinical outcomes when integrated into multi-modality professional protocols.

Professional Use Only

Multi-Component Biostimulating Cocktail developed for dermal remodeling and optimization of the dermal-epidermal junction.

Indicated as an adjuvant within professional rejuvenation protocols targeting:

  • Photoaging
  • Loss of density
  • Incipient skin laxity
  • Fine lines
  • Irregular skin texture

It may also be incorporated into combined professional plans designed for:

  • Atrophic acne scars
  • Stretch marks

Use according to professional clinical evaluation and discretion.

Presentation

5 ml single-dose sterile vial
Box containing 5 sterile vials.

Professional Guidelines

Recommended protocol:

  • Fortnightly sessions for 2 months
  • 1 vial per session
  • From the third month onward, maintenance according to clinical response and professional prescription

Ingredients

Active Ingredients

  • Human-like Growth Factors:
    EGF, TGF-β2, and VEGF work synergistically to support epidermal renewal, dermal remodeling, fibroblast activity, and tissue revitalization.
  • Human-like Biomimetic Fragments:
    Collagen I, Collagen IV, and Fibrillin-1 provide structural support and help reinforce dermal-epidermal cohesion, elasticity, and matrix organization.
  • Skinarch™ Peptide:
    Advanced peptide technology designed to support fibrillar collagen architecture, promoting improved firmness, skin density, and structural integrity.

Technology

Technology & Mechanism of Action

BIOGF 331 integrates active ingredients with complementary biological targets designed to support dermal regeneration, matrix organization, and overall skin quality optimization.

  • Epidermal Signaling (EGF):
    Supports epidermal renewal processes and reinforces skin barrier function, contributing to smoother, healthier-looking skin.
  • Dermal Signaling (TGF-β2):
    Helps modulate fibroblast activity and supports extracellular matrix synthesis, promoting improved dermal structure and firmness.
  • Microvascular Support (VEGF):
    Contributes to a favorable tissue microenvironment that supports repair, remodeling, and skin revitalization processes.
  • Biomimetic Structural Fragments:
    Human-like Collagen I, Collagen IV, and Fibrillin-1 provide structural “building blocks” and anchoring points that help reinforce mechanotransduction and dermal-epidermal cohesion.
  • Skinarch™ Technology:
    Acts as a fibrillar collagen “architect,” promoting better-organized collagen fibers through the Mohawk signaling axis and Collagen VI support, helping optimize dermal structure and elasticity.

Expected Clinical Outcome

  • Progressive improvement in dermal firmness and density
  • Optimization of skin texture and luminosity through reinforcement of the dermal-epidermal junction (DEJ)
  • Enhanced skin elasticity and “bounce” through support of the elastic fiber network
  • Improved overall skin quality and structural coherence
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BIOGF 331 - Sterilia 5ml

BIOGF 331 - Sterilia 5ml