Description
Multi-Axis Dermal Biostimulation
A sterile formulation engineered to optimize skin quality through the synergistic combination of human-like growth factors (EGF, TGF-β2, and VEGF) together with human-like biomimetic fragments of Collagen I, Collagen IV, and Fibrillin-1.
The formula also incorporates Skinarch™, an advanced modulator of fibrillar collagen architecture designed to support matrix organization and dermal integrity.
This comprehensive approach targets the three essential pillars of aesthetic regeneration:
- Cellular signaling
- Structural substrate support
- Extracellular matrix organization
In both intrinsic aging and photoaging, there is a progressive reduction in collagen synthesis, increased degradation by Matrix Metalloproteinases (MMPs), oxidative stress accumulation, and deterioration of the dermal-epidermal junction (DEJ).
BIOGF 331 is designed as an adjuvant solution to help restore skin density, firmness, and elasticity while improving the coherence and quality of clinical outcomes when integrated into multi-modality professional protocols.
Professional Use Only
Multi-Component Biostimulating Cocktail developed for dermal remodeling and optimization of the dermal-epidermal junction.
Indicated as an adjuvant within professional rejuvenation protocols targeting:
- Photoaging
- Loss of density
- Incipient skin laxity
- Fine lines
- Irregular skin texture
It may also be incorporated into combined professional plans designed for:
- Atrophic acne scars
- Stretch marks
Use according to professional clinical evaluation and discretion.
Presentation
5 ml single-dose sterile vial
Box containing 5 sterile vials.
Professional Guidelines
Recommended protocol:
- Fortnightly sessions for 2 months
- 1 vial per session
- From the third month onward, maintenance according to clinical response and professional prescription









